Set up in 2002 and headed by Prof. David Cranston

牛津大學丘吉爾醫院HIFU中心，中心臨床主任 David Cranston 教授，建立于2002年

An excellent clinical team consisting of experts of 8 specialities.

中心目前有8個臨床團隊在開展不同的HIFU適應癥，包括HIFU治療婦科良性疾病、肉瘤、前列腺癌、神經外科、胰腺癌、乳腺癌，以及聚焦超聲誘導藥物遞送。

Oxford HIFU Group has set numerous milestones in the exploration in HIFU therapy.

July 2019, HIFU therapy for uterine fibroids entered the NICE guideline in the UK. 

牛津HIFU團隊創下了多項HIFU推廣應用里程碑

2019年HIFU治療子宮肌瘤正式進入英國NICE指南

www.nice.org.uk/guidance/ipg657

July 2018, “Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial” revealed satisfying clinical outcomes.

2018年發表了聚焦超聲誘導藥物遞送治療肝癌文章 

http://dx.doi.org/10.1016/S1470-2045(18)30332-2

April 2017, the 20-center research result through the joint efforts of the Surgical Intervention Trials Unit of Oxford University, the National Engineering Research Centre for Ultrasound Medicine, Chongqing China, the Chinese Cochrane Centre, 20 participating centres, and 2411 fibroid patients was published. 

2017年協同超聲醫療國家工程研究中心、中國循證醫學中心、20家中國醫院和20411名患者發表了前瞻性多中心HIFU治療子宮肌瘤研究結果。

https://doi.org/10.1111/1471-0528.14689

Dec. 2016, a series of four cases proved that high-intensity focused ultrasonic ablation of sacral chordoma is feasible. 

2016年發表了HIFU治療骶骨脊索瘤的可行性研究結果

https://doi.org/10.1080/02688697.2016.1267330

June 2005, European Community’s approval (CE 0197) of Chongqing HAIFU for treating liver and kidney malignancy after clinical treatment of about 50 patients in Churchill Hospital.

2005年，在牛津開展的HIFU治療50余名患者使海扶聚焦超聲腫瘤治療設備成功拿到CE認證。

More indications for HIFU are being explored in Oxford by this great team. 

牛津HIFU中心團隊在探索HIFU應用上砥礪前行

https://www.nds.ox.ac.uk/research/hifu

For more published scientific papers, please check the literature list.

更多牛津HIFU中發表的文章可查看以下文獻列表：

1.  Kennedy JE, Ter Haar GR, Cranston D. High intensity focused ultrasound: surgery of the future? Br J Radiol. 2003 Sep;76(909):590-9.

2.    Kennedy JE, ter Haar GR, Wu F, Gleeson FV, Roberts IS, Middleton MR, et al. Contrast-enhanced ultrasound assessment of tissue response to high-intensity focused ultrasound. Ultrasound Med Biol. 2004 Jun;30(6):851-4.

3.    Kennedy JE, Wu F, ter Haar GR, Gleeson FV, Phillips RR, Middleton MR, et al. High-intensity focused ultrasound for the treatment of liver tumours. Ultrasonics. 2004 Apr;42(1-9):931-5.

4.    Illing RO, Kennedy JE, Wu F, ter Haar GR, Protheroe AS, Friend PJ, et al. The safety and feasibility of extracorporeal high-intensity focused ultrasound (HIFU) for the treatment of liver and kidney tumours in a Western population. Br J Cancer. 2005 Oct 17;93(8):890-5.

5.    Kennedy JE. High-intensity focused ultrasound in the treatment of solid tumours. Nat Rev Cancer. 2005 Apr;5(4):321-7.

6.    Marberger M, Schatzl G, Cranston D, Kennedy JE. Extracorporeal ablation of renal tumours with high-intensity focused ultrasound. BJU Int. 2005 Mar;95 Suppl 2:52-5.

7.    Illing R, Leslie T, Kennedy J, Wu F, Ter Haar G, Phillips R, et al. HIGH-INTENSITY FOCUSED ULTRASOUND FOR THE TREATMENT OF SMALL RENAL TUMOURS. European Urology Supplements. 2006;5(2):218-.

8.    Illing RO, Leslie TA, Kennedy JE, Calleary JG, Ogden CW, Emberton M. Visually directed high-intensity focused ultrasound for organ-confined prostate cancer: A proposed standard for the conduct of therapy. BJU Int. 2006 Dec;98(6):1187-92.

9.    Leslie TA, Illing RO, Kennedy JE, Wu F, ter Haar GR, Phillips RR, et al. PD-08.02: High intensity focused ultrasound for the treatment of small renal tumours. Phase II trial results from Oxford. Urology. 2006;68(Supplement 1):28

10.  Leslie TA, Kennedy JE. High-intensity focused ultrasound principles, current uses, and potential for the future. Ultrasound Q. 2006 Dec;22(4):263-72.

11.  Calleary J, Leslie T, Iling R, Ahmed H, Kennedy J, Brewster S, et al. 707 HIGH INTENSITY FOCUSE

12.    Kennedy JE, Ter Haar GR, Cranston D. High intensity focused ultrasound: surgery of the future? Br J Radiol. 2003 Sep;76(909):590-9.

13.    Kennedy JE, ter Haar GR, Wu F, Gleeson FV, Roberts IS, Middleton MR, et al. Contrast-enhanced ultrasound assessment of tissue response to high-intensity focused ultrasound. Ultrasound Med Biol. 2004 Jun;30(6):851-4.

14.    Kennedy JE, Wu F, ter Haar GR, Gleeson FV, Phillips RR, Middleton MR, et al. High-intensity focused ultrasound for the treatment of liver tumours. Ultrasonics. 2004 Apr;42(1-9):931-5.

15.    Illing RO, Kennedy JE, Wu F, ter Haar GR, Protheroe AS, Friend PJ, et al. The safety and feasibility of extracorporeal high-intensity focused ultrasound (HIFU) for the treatment of liver and kidney tumours in a Western population. Br J Cancer. 2005 Oct 17;93(8):890-5.

16.    Kennedy JE. High-intensity focused ultrasound in the treatment of solid tumours. Nat Rev Cancer. 2005 Apr;5(4):321-7.

17.    Marberger M, Schatzl G, Cranston D, Kennedy JE. Extracorporeal ablation of renal tumours with high-intensity focused ultrasound. BJU Int. 2005 Mar;95 Suppl 2:52-5.

18.    Illing R, Leslie T, Kennedy J, Wu F, Ter Haar G, Phillips R, et al. HIGH-INTENSITY FOCUSED ULTRASOUND FOR THE TREATMENT OF SMALL RENAL TUMOURS. European Urology Supplements. 2006;5(2):218-.

19.    Illing RO, Leslie TA, Kennedy JE, Calleary JG, Ogden CW, Emberton M. Visually directed high-intensity focused ultrasound for organ-confined prostate cancer: A proposed standard for the conduct of therapy. BJU Int. 2006 Dec;98(6):1187-92.

20.    Leslie TA, Illing RO, Kennedy JE, Wu F, ter Haar GR, Phillips RR, et al. PD-08.02: High intensity focused ultrasound for the treatment of small renal tumours. Phase II trial results from Oxford. Urology. 2006;68(Supplement 1):28

21.  Leslie TA, Kennedy JE. High-intensity focused ultrasound principles, current uses, and potential for the future. Ultrasound Q. 2006 Dec;22(4):263-72.

22.  Calleary J, Leslie T, Iling R, Ahmed H, Kennedy J, Brewster S, et al. 707 HIGH INTENSITY FOCUS

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